WELCOME TO OUR RESEARCH GROUP....
Research interests and some accomplishments:
inorganic-, and biochemistry: Laws of thermodynamics and
quantum mechanics applied to chemical problems
of importance. The structure, dynamics, function,
and natural evolution of proteins.
identify the molecular causes of neurological
diseases such as Alzheimer's Disease and ALS, to
design molecular systems of interest and value.
Some main findings:
|June 2018: Welcome to
Budheswar, who will work as a postdoc on predicting
Alzheimer's disease-causing mutations
|May 2018: Humble thanks to DFF and the Danish taxpayers for supporting our project on developing new protein stability prediction tools|
|May 2018: Kasper
silently celebrates his 100th review report for ACS in
the Paragon Plus System.
|April-May 2018: Kasper
is on family leave from work.
|Feb 1, 2018. Ning Tang
joins as DFF postdoctoral fellow working on new medicine
targeting gamma secretase in Alzheimer's disease.
|Jan 1, 2018. Rukmankesh
will join our group to study laccases in collaboration
with Prof. Anne Meyer, DTU Chemical Engineering -
|Dec 12, 2017. Arun
defends his ph.d. thesis on proteins in Alzheimer's
|Dec 7, 2017. NNF awards us funding for our project that will explore the causes and disease properties of mutations in Alzheimer's disease. Thanks!|
|July 4, 2017. Kasper speaks at the EICC4 conference|
|May 8, 2017. Kasper will speak at the Danish Annual meeting for Neuroscience|
|May 8, 2017. DFF funds
our research into the mechanism and new treatments
targeting the protein gamma secretase (commence 2018)
|March 2017. Review of heme's amazing chemical properties and role in life is out.|
|Feb 2017. Benchmarking DFT for gold: First detailed benchmark of DFT's ability to describe diverse chemical bonds to gold|
|Jul 2016. Kasper
speaks at the ICPP
conference in Nanjing, China, on heme
|Jun 2016. Loss
of function in Alzheimer's Disease. A
comprehensive explanation why current clinical trials
|Apr 2016. Protein stability effects are universal and can predict stabilities of protein variants relevant to protein engineering and evolution.|
|Feb 2016. The general
mess of Aβ. New
meta-analysis shows no relationship between cell
and mouse data and clinical outcome, i.e. do not reflect
aging human AD.
|Sep 2015. The quest for the structure of β-amyloid (new work published in ChemPhysChem)|
|Aug 2015. Speaking
at the ECOSTBio meeting in Belgrade, Aug 24-25.
|July 2015. Speaking at the ICCB conference in Kauai, Hawaii, July 2 to 6.|
|June 2015. EMBO neuro- degeneration meeting in Heidelberg June 14-17.|
|March 2015. Molecular Causes of ALS: Coupling protein energy to real patient data.|
|Feb 2015. New mechanism of laccase inhibition: impairing reorganization energies.|
|Nov 2014. New patent WO2014167112 for synthesizing sugars|
|Nov 2014. First relation between patient data and chemical properties of genetic variants causing Alzheimer's disease|
|Oct 2014. Søren Brander defends his Ph.D. Congratulations!|
|Sep 2014. Arun joins our group as a ph.d. student to work on proteins involved in Alzheimer's disease.|
|Dec 2013. Kasper joins the Management commitee of the COST action on spin states in biochemistry and technology|
|Jun 2013. Pouria Dasmeh successfully defends his Ph.D. Congratulations!|
|Dec 2012. Our research is described in the Danish newspaper Politiken.|
|Oct 2012. New review in Chemical Reviews on "Bioinorganic Chemistry of Alzheimer's Disease"|
|Sep 2012. Kasper speaks at the CECAM workshop in Zaragoza, Sep 18-21.|
|Aug 2012. New review on "Consistent descriptions of metal–ligand bonds and spin-crossover in inorganic chemistry"|
|Copyright 2014. Kasper P. Kepp.|